In the third season premiere, a skull smashes through the windshield of some teenagers’ car while they’re driving on the freeway. While examining the skull, Brennan and Cam find marks on it made by human teeth, which implies cannibalism. Identifying the victim, Brennan and Booth go out to investigate, discovering a weird cannibalistic society as they try to solve the case. Meanwhile, Angela and Hodgins hire a private investigator to find her husband. Also, Zack returns to the Jeffersonian, and finds some crucial evidence to help solve the case.

The Gormogon serial killer is back again, and the silver skeleton from the basement vault has gone missing. All the Jeffersonian employees become suspects, with the scary possibility that one of their own is working with Gormogon.